Multiple Schwannomas in Sciatic Nerve: A Rare Case Report

Document Type : CASE REPORT


1 Department of Orthopaedic Surgery, Iran University of Medical Sciences, Tehran, Iran

2 Department of Orthopaedic Surgery, Rasoul-E-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran

3 University of Texas Health Science Center, Houston, USA

4 Iran University of Medical Sciences, Tehran, Iran


Schwannomas are the most common nerve sheath tumors which are usually solitary enucleated lesions. Multiple
schwannomas are a rare circumstance which may occur with or without other manifestations of neurofibromatosis.
In this study, we report the case of a 45-year-old man presenting with pain and swelling in the thigh and popliteal space
without any manifestation of neurofibromatosis or neurologic problems. Surgery was performed and revealed four
separated tumors in the sciatic nerve which was characteristic of schwannoma and confirmed by pathologic findings.
Although multiple schwannomas are frequently associated with neurofibromatosis, the current case demonstrated
a patient with multiple schwannomas without any manifestation o f neurofibromatosis.
Level of evidence: IV


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Volume 9, Issue 5
September and October 2021
Pages 601-604
  • Receive Date: 30 October 2020
  • Accept Date: 23 February 2021
  • First Publish Date: 02 March 2021