Document Type : RESEARCH PAPER
Authors
1
10- Anesthetic Practitioner at University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
2
1- Department of neurosurgery, Urmia University of Medical Sciences, Urmia, Iran.
3
2- Thunderbird School of Arizona State University, Tempe Campus, Phoenix, Arizona 85004, USA
4
4- Department of anesthesiology, Urmia University of Medical Sciences, Urmia, Iran.
5
5- Biomedical Department, Al-Mustaqbal University, Hillah 51001, Babil, Iraq.
6
6- Orthopedic and spine consultant, Taif university, Kingdom of Saudi Arabia.
7
7- College of pharmacy, the Islamic University, Najaf, Iraq
8
8- Department of Medicine, AL-Nisour University College/ Baghdad/ Iraq
9
9- College of Health and Medical, National University of Science and Technology, Dhi Qar, Iraq
10
1- Department of neurosurgery, Urmia University of Medical Sciences, Urmia, Iran
10.22038/abjs.2025.89179.4044
Abstract
Objective: This study aimed to compare the effect of epidural gel foam impregnated with bupivacaine and intramuscular paravertebral bupivacaine on analgesia after lumbar spine surgeries.
Methods: In this single-blind clinical trial study, 60 patients aged 18 to 65 years undergoing lumbar spine surgery with general anesthesia were divided into two groups: for patients in one group, a 1 x 5 cm strip of gel-foam impregnated with 70 mg Bupivacaine 0. 5% was placed in the epidural space, and for patients in the second group, 70 mg Bupivacaine 0. 5% was injected intramuscularly paravertebrally. Pain scores based on VAS, pain medication prescription, first analgesic request, and dosage during recovery, 6, 12, and 24 hours after the operation were measured and compared between the two groups.
Results: There was no significant difference in the average pain scores at different stages of measurement (Recovery, 6, and 12 hours) between the two groups (P ˃ 0.05). But within 24 hours after surgery, a significant difference was evident between the two groups, so that the VAS score in the bupivacaine-impregnated epidural gel foam group was significantly lower than the paravertebral intramuscular bupivacaine group (P= 0.04).
Conclusion: Bupivacaine-impregnated epidural gel-foam and paravertebral intramuscular bupivacaine provide similar analgesia during recovery and 6 and 12 hours after spinal surgeries, but at 24 hours, the analgesia of the bupivacaine-impregnated epidural gel-foam group is more than the paravertebral intramuscular bupivacaine group.
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