Review on Prevalence of Periprosthetic Joint Infection Following Joint Arthroplasty

Document Type : CURRENT CONCEPTS REVIEW

Authors

1 Orthopedic Research Center, Department of Orthopedic Surgery, Mashhad University of Medical Science, P. O. Box 91388-13944, Mashhad, Iran

2 Orthopedics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Ghaem Hospital Orthopedic Research Center, Mashhad University of Medical Science

10.22038/abjs.2025.81816.3726

Abstract

Periprosthetic joint infection (PJI) is a serious complication that can occur after joint arthroplasty, significantly affecting both the healthcare system and patients due to high costs and mortality rates. Managing PJI is complex and presents significant challenges in orthopedic surgery because there is no standardized definition for PJI and no universally accepted diagnostic gold standard. Despite various preventive measures taken before and during surgery, PJIs still occur. Many treatment options are available, but the best management is still highly debated, and the best treatment choice depends on several factors. Notably, all of these treatments are taken after the occurrence of PJI, while modern strategies, such as coating methods with various materials, must be relied upon to control and prevent the occurrence of PJI. This review focuses on the precise concept of PJIs, treatment options, and novel strategies to prevent PJIs.

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Articles in Press, Accepted Manuscript
Available Online from 07 May 2025
  • Receive Date: 10 August 2024
  • Revise Date: 28 April 2025
  • Accept Date: 22 February 2025