Primary Total Knee Arthroplasty in Hemophilia and Allied Disorders: Revision Rates and Their Causes

Document Type : In Brief

Author

Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

Abstract

When patients with hemophilia and allied disorders (von Willebrand disease and other congenital 
bleeding disorders) do not receive adequate primary hematologic prophylaxis from infancy, their joints 
will suffer knee joint degeneration; when such joint degeneration becomes very advanced (painful and 
disabling) despite previous conservative treatment, the only way to alleviate the problem will be to 
implant a primary total knee arthroplasty (TKA). The literature has shown that twenty years after 
implantation, 71% of primary TKAs are still functional; on the other hand, 18% have to be revised as a 
consequence of periprosthetic joint infection (PJI). The main causes of revision total knee arthroplasty 
are PJI and aseptic loosening (39% each).
 Level of evidence: III

Keywords

Main Subjects


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