Document Type : RESEARCH PAPER
Department of Neurosurgery, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
2 Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran 3 Clinical Research Development Unit, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Operating Room, School of Nursing, North Khorasan University of Medical Sciences, Bojnurd, Iran
Department of Neurosurgery, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran
Department of Neurosurgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Nursing, School of Nursing, North Khorasan University of Medical Sciences, Bojnurd, Iran
Objectives: Effective postoperative pain control in microdiscectomy surgery is crucial to managing the
disease and improving the patient's quality of life. Therefore, this study aimed to assess the potential
effectiveness of 2% lidocaine in reducing pain immediately after discectomy surgery.
Methods: A total of 60 patients who underwent microdiscectomy surgery were enrolled in this randomized clinical
trial study. They were randomly assigned to three groups: one group received lidocaine just before the incision,
another group received lidocaine just before closing the incision, and the third group served as the control. Pain
scores were measured at 1, 2, 3, 4, 8, and 12 h after the surgery using a Visual Analogue Scale.
Results: The demographic and clinical characteristics of the study population, including age, weight, length of
surgery, gender, and history of diabetes, hypertension, and previous surgery, were comparable across all three
groups (P>0.05). There was a significant reduction in pain scores over time in the groups that received lidocaine
before (P<0.001) and during surgery (P=0.002). Moreover, there were significant differences in pain scores at all
time points among the three groups. Both groups receiving lidocaine showed significantly lower pain scores than
the control group (Pbefore surgery=0.005 and Pduring surgery<0.001). However, no significant difference was
observed between the groups receiving lidocaine (P=0.080).
Conclusion: These findings highlight the effectiveness of a local injection of 2% lidocaine either before or during
the surgery in managing post-incisional surgical pain after discectomy.
Level of evidence: II