Document Type : RESEARCH PAPER
Department of Orthopaedic Surgery, Joan C. Edwards school of medicine, Marshall University, Huntington, WV, Huntington, West Virginia, USA
University of Calgary, Calgary, Alberta, Canada
Department of Orthopedic Surgery, Boston University, Boston VAMC, Boston, Massachusetts, USA
School of Medicine, University of Texas medical Branch,Texas, USA
Department of Orthopedic Surgery, University of Texas Southwestern, Dallas VAMC, Dallas, Texas, USA
Background: Parkinson’s Disease is a well-known neuromuscular disorder, which affects the stability and gait of
elderly patients. With the progressive increase in the life span of patients with PD, the problem of degenerative
arthritis and the consequent need for total hip arthroplasty (THA) in this cohort are rising. There is paucity of data in
the existing literature regarding the healthcare costs and overall outcome following THA in PD patients. The current
study was planned to assess the hospital expenditure, details regarding hospital stay, and complication rates for
patients with PD, who underwent THA.
Methods: We investigated the National Inpatient Sample data to identify PD patients, who underwent hip
arthroplasty from 2016 to 2019. Using propensity score, PD patients were matched 1:1 to patients without PD by
age, gender, non-elective admission, tobacco use, diabetes, and obesity. Chi-square and T-tests were used for
analyzing categorical and non-categorical variables, respectively (Fischer-Exact test was employed for values<5).
Results: Overall, 367,890 (1927 patients with PD) THAs were performed between 2016 and 2019. Before matching,
PD group had significantly greater proportion of older patients, males, and non-elective admissions for THA (P<0.001).
After matching, PD group had higher total hospital costs, longer hospital stay, greater blood loss anemia, and prosthetic
dislocation (P<0.001). The in-hospital mortality was similar between the two groups.
Conclusion: Patients with PD undergoing THA required greater proportion of emergent hospital admissions. Based on
our study, the diagnosis of PD showed significant association with greater cost of care, longer hospital stay, and higher
Level of evidence: II