Culture-negative Peri-prosthetic Joint Infection after Total Hip Arthroplasty. Treatment Protocol and Outcomes in Acute and Chronic Cases



1 Department of Orthopaedic and Traumatology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina

2 Department of Infectology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina


The treatment of culture-negative periprosthetic joint infections (CN PJI) of the hip represents complex entities. We, as a 
result of this, report on 12 cases. Irrigation and debridement (I&D) with implant retention were performed in acute cases 
and two-stage revisions in chronic infections. Combined antibiotic therapy was administered in all cases for 12 weeks. 
Infection control was achieved in all patients with an infection-free rate of 100% at 7.5 years of average follow-up.
Level of evidence: IV


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