The Archives of Bone and Joint Surgery

The Archives of Bone and Joint Surgery

Fetal Rhabdomyoma of the upper Extremity in a 31- Year Old Patient: a Case Report

Document Type : CASE REPORT

Authors
Georg Hauer 1
Jörg Friesenbichler 1
Franz Gollowitsch 2
Andreas Leithner 1
Lukas A. Holzer 3
1 Department of Orthopaedics and Traumatology, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria
2 Institute of Pathology, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria
3 AUVA Trauma Center Klagenfurt, Waidmannsdorferstraße 35, Klagenfurt am Wörthersee, Austria Department of Orthopaedics and Traumatology, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria
10.22038/abjs.2018.30742.1798
Abstract
Fetal rhabdomyomas (RM) are extremely rare benign mesenchymal tumours that occur primarily in the head and neck.
This tumour exhibits immature skeletal muscle differentiation. The patients’ median age is four years and surgical resection
is the recommended treatment.
Fetal RM of limbs are rare and not well described in the literature and if, predominantly in form of case reports. We report
the second case of a fetal RM in the upper extremity in a 31-year old male patient.
One should be aware of this skeletal muscle tumour and fetal RM should be considered as a differential diagnosis to its
malignant counterpart rhabdomyosarcoma.
Level of evidence: V
Keywords
Fetal
Rhabdomyoma
Rhabdomyosarcoma
Tumour
Subjects
1. Kapadia SB, Meis JM, Frisman DM, Ellis GL, Heffner
DK. Fetal rhabdomyoma of the head and neck: a
clinicopathologic and immunophenotypic study of 24
cases. Hum Pathol. 1993; 24(7):754-65.
2. Osgood PJ, Damron TA, Rooney MT, Goldschmidt AM,
Sullivan TJ. Benign fetal rhabdomyoma of the upper
extremity. A case report. Clin Orthop Relat Res. 1998;
349(1):200-4.
3. Willis J, Abdul-Karim FW, di Sant’Agnese PA.
Extracardiac rhabdomyomas. Semin Diagn Pathol.
1994; 11(1):15-25.
4. Dehner LP, Enzinger FM, Font RL. Fetal rhabdomyoma.
An analysis of nine cases. Cancer. 1972; 30(1):160-6.
5. Premalata CS, Kumar RV, Saleem KM, Fathima LJ, Das
K. Fetal rhabdomyoma of the lower extremity. Pediatr
Blood Cancer. 2009; 52(7):881-3.
6. Weiss SW, Goldblum JR. Enzinger and Weiss’s soft
tissue tumors. 5th ed. New York: Mosby Elsevier;
2008.
7. Kodet R, Fajstavr J, Kabelka Z, Koutecky J, Eckschlager
T, Newton WA Jr. Is fetal cellular rhabdomyoma an
entity or a differentiated rhabdomyosarcoma? A
study of patients with rhabdomyoma of the tongue
and sarcoma of the tongue enrolled in the intergroup
rhabdomyosarcoma studies I, II, and III. Cancer. 1991;
67(11):2907-13.
8. Tuazon R. Rhabdomyoma of the stomach. Report of a
case. Am J Clin Pathol. 1969; 52(1):37-41.
9. Whitten RO, Benjamin DR. Rhabdomyoma of the
retroperitoneum. A report of a tumor with both adult
and fetal characteristics: a study by light and electron
microscopy, histochemistry, and immunochemistry.
Cancer. 1987; 59(4):818-24.
10. Dahl I, Angervall L, Save-Soderbergh J. Foetal
rhabdomyoma. Case report of a patient with two
tumours. Acta Pathol Microbiol Scand A. 1976;
84(1):107-12.
11. DiSanto S, Abt AB, Boal DK, Krummel TM. Fetal
rhabdomyoma and nevoid basal cell carcinoma
syndrome. Pediatr Pathol. 1992; 12(3):441-7.
The Archives of Bone and Joint Surgery
Volume 7, Issue 2
March and April 2019
Pages 199-202

  • Receive Date 12 April 2018
  • Revise Date 29 May 2018
  • Accept Date 02 June 2018