Angioleiomyoma of the Hand: A Case Series and Review of the Literature



Division of Orthopaedic Oncology, Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA


Background: Angioleiomyomas are rare tumors arising from vascular tissue that can occasionally present in the hand.
Reports of angioleiomyomas in this location are highly limited. Here, we describe the presentation and outcomes of a
series of cases of angioleiomyomas.
Methods: A retrospective case review of five patients with angioleiomyomas arising in the hand was performed. Patients
were identified via International Classification of Diseases, Ninth and Tenth Revision (ICD-9 and ICD-10) diagnosis
codes and were reviewed through the electronic medical record for demographic information, tumor characteristics,
management, and outcomes. A literature review was also conducted of angioleiomyomas.
Results: Five patients were diagnosed with angioleiomyoma at our institution between 1992 and 2015. Patients
presented with a painful, slow-growing hand mass in all cases. The majority of patients were male and of middle-age.
All of the patients were successfully treated with marginal excision and had full return to functional status without
Conclusion: Angioleiomyomas are rare tumors that can arise in the hand and should be included in the differential
diagnosis of a patient presenting with a painful hand mass. They can be successfully treated with marginal excision.
Level of evidence: IV