Creep behavior of Biodegradable Triple-component Nanocomposites Based on PLA/PCL/bioactive Glass for ACL Interference Screws



1 Orthopedic Research Center, Mashhad University of Medical Science, Mashhad, Iran Esfarayen University of Technology, Esfarayen, North Khorasan, Iran

2 Biomaterials Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Tehran, Iran

3 Orthopedic Research Center, Mashhad University of Medical Science, Mashhad, Iran

4 Central Laboratory Faculty, Iran Polymers and Petrochemical Institute, Tehran, Iran


Background: Short-time creep behaviorfor aseries of biodegradable nanocomposites, which areused as implantable
devices inthe body, is a crucial factor.The present study aimed to investigate the effect of bioactive glass nanoparticles
(BGn) on creep and creep-recovery behaviors of polylactic acid/polycaprolactone (PLA/PCL) blends at different given
loads and different applied temperatures.
Methods: A series of biodegradable nanocomposites consisted of PLA/PCL blends (comprising 80 parts PLA and 20
parts PCL) with different amounts of modified-BGn (m-BGn) fillers were prepared using the evaporated solvent casting
technique. Creep and creep-recovery behaviors of all specimens were studied at different valuable stressesof 3 and 6
MPa and different given temperatures of 25 and 37°C.
Results: In all cases, m-BGn improved the creep resistance of the nanocomposites due to the retardation effect
during the creep behaviors of the nanocomposite systems. The obtained results in terms of creep and creep-recovery
properties determined that the nanocomposites of PLA/PCL/m-BGn can satisfy the required conditions of an appropriate
anterior cruciate ligament reconstruction (ACL-R) screw.
Conclusion: The obtained results confirmed that the BGn plays an impeding role in the movement of PLA/PCL chains
leading to in increase the creep resistance. According to the results, it was determined that the nanocomposites of PLA/
PCL and m-BGn can satisfy the required circumstances of a proper ACL-R screw.
Level of evidence: I


Main Subjects