<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>The Archives of Bone and Joint Surgery</title>
			<title_fa></title_fa>
			<short_title>ABJS</short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://abjs.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn>2345-4644</journal_id_issn>
			<journal_id_issn_online>2345-461X</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year>0</year>
				<month>0</month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year>2018</year>
				<month>11</month>
				<day>1</day>
			</pubdate>
			<volume>6</volume>
			<number>6</number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Effects of Zoledronic Acid and Vitamin E on Surgical– Induced Osteonecrosis of the Femoral Head in Rabbit</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>RESEARCH PAPER</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Background: Femoral head osteonecrosis is a progressive disease with disabling outcomes in hip joint if not treated.This study was designed to compare the effects of zoledronic acid plus vitamin E versus zoledronic acid alone insurgical induced femoral head osteonecrosis in rabbits.Methods: 26 Japanese white adult normal male rabbits at 28-32 weeks old were undertaken surgical femoraldislocation to devastate the femoral neck vessels; the femoral neck vessels were ligated and the hip was relocated.Next, the first 10 rabbits received zoledronic acid injections at 1st and the 4th weeks; the second group (10 rabbits)received zoledronic acid injections at 1st and the 4th week along with daily oral vitamin E for 12 weeks; and thethird group was considered as non-treated control group. Radiographic and postmortem pathological assessmentsincluding the Ficat classification, epiphyseal quotient (EQ), new bone formation, and residual necrotic bone (RNB)were performed and compared after week 12.Results: A significant difference was found between the combination therapy group and the control group in Ficatclassification at 12th weeks (P=0.048), but, the difference between monotherapy and combination therapy groups at12th weeks was nonsignificant (P=0.37). Also, both treated groups had significant difference with the control group forRNB (P=0.015). There were no significant differences between the three groups for Ficat classification at the 6th week(P=0.65); EQ at 6th (P=0.59) and 12th week (P=0.64); and NBF (P=0.55).Conclusion: Although zoledronic acid therapy along with vitamin E could improve some radiologic and pathologicalindices related to femoral head osteonecrosis, vitamin E showed a relative impact.Level of evidence: I]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>ONFH, Osteonecrosis of femoral head, Vitamin E, Zoledronic acid</keyword>
				<start_page>547</start_page>
				<end_page>553</end_page>
				<web_url>https://abjs.mums.ac.ir/article_10293.html</web_url>
			<author_list><author>
				<first_name>Kaveh</first_name>
				<middle_name></middle_name>
				<last_name>Gharanizadeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>kaveh.gharani@gmail.com</email>
				<code>42851</code>
				<coreauthor>No</coreauthor>
				<affiliation>Bone and Joint Reconstruction Research Center, Shafa
Orthopedic Hospital, Iran University of Medical Sciences
(IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Sina</first_name>
				<middle_name></middle_name>
				<last_name>Aminizadeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>dr.s.aminizadeh@gmail.com</email>
				<code>42852</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Bone and Joint Reconstruction Research Center, Shafa
Orthopedic Hospital, Iran University of Medical Sciences
(IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Nima</first_name>
				<middle_name></middle_name>
				<last_name>Molavi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>nm.molavi@gmail.com</email>
				<code>42853</code>
				<coreauthor>No</coreauthor>
				<affiliation>Bone and Joint Reconstruction Research Center, Shafa
Orthopedic Hospital, Iran University of Medical Sciences
(IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Amir</first_name>
				<middle_name></middle_name>
				<last_name>Darbandi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>amir.doc60@gmail.com</email>
				<code>42854</code>
				<coreauthor>No</coreauthor>
				<affiliation>Rajaie Cardiovascular, Medical and Research Centre, Iran
University of Medical Sciences (IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Shabnam</first_name>
				<middle_name></middle_name>
				<last_name>Nadjafi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>najafi.sh@iums.ac.ir</email>
				<code>42855</code>
				<coreauthor>No</coreauthor>
				<affiliation>Iran University of Medical Sciences (IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mahsa</first_name>
				<middle_name></middle_name>
				<last_name>Fadavighaffari</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mahsafadavimsc93@gmail.com</email>
				<code>42856</code>
				<coreauthor>No</coreauthor>
				<affiliation>Iran University of Medical Sciences (IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Tina</first_name>
				<middle_name></middle_name>
				<last_name>Shooshtarizadeh</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>tinashooshtarizadeh@gmail.com</email>
				<code>42857</code>
				<coreauthor>No</coreauthor>
				<affiliation>Bone and Joint Reconstruction Research Center, Shafa
Orthopedic Hospital, Iran University of Medical Sciences
(IUMS), Tehran, Iran</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>