@article { author = {Fernando, Navin and Werner, Shawn and Elhaddad, Moamen and Davies, Jonah and Firoozabadi, Reza}, title = {Do Antibiotic Beads Need to be Removed?}, journal = {The Archives of Bone and Joint Surgery}, volume = {8}, number = {4}, pages = {502-505}, year = {2020}, publisher = {Mashhad University of Medical Sciences, Iranian Society of Knee Surgery, Arthroscopy and Sports Tramatology,Iranian Orthopaedic Association}, issn = {2345-4644}, eissn = {2345-461X}, doi = {10.22038/abjs.2020.44143.2208}, abstract = {Background: Polymethylmethacrylate antibiotic impregnated beads can be an effective treatment for chronicosteomyelitis or an adjuvant in the treatment of open fractures. It remains unclear however whether the beads causelong-term adverse events if not removed. The purpose of this study was to determine if removal of antibiotic beads wasrequired in order to avoid long term complications.Methods: A retrospective chart review was conducted on patients with an extremity or pelvis fracture that hadimplantation of polymethylmethacrylate (PMMA) antibiotic beads over a five-year period.Results: Fifty-one patients met inclusion criteria for this study; thirty-seven patients (73%) did not have complicationsafter surgical debridement and placement of PMMA antibiotic beads necessitating removal.Conclusion: Our findings suggest that polymethylmethacrylate antibiotic beads can be utilized as a means of deliveringhigh-dose concentrations of local antibiotics and do not have to be removed in all patients.Level of evidence: III}, keywords = {Antibiotics,antibiotic beads,Antibiotic resistance,Fracture,Infection}, url = {https://abjs.mums.ac.ir/article_16110.html}, eprint = {https://abjs.mums.ac.ir/article_16110_9c43f560fe4b918748ce1d269344d874.pdf} }