Document Type: CASE REPORT

Authors

1 Orthopedics Department, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

2 Department of Pathology, Cancer Institute, Imam Hospital Complex, Tehran university of Medical Sciences, Tehran, Iran

3 Orthopedics Department, Imam Hospital Complex, Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran Iran

Abstract

Malignant transformation of glomus tumor is exceedingly rare and most common reported in lower extremity and abdominal
viscera. We could find only 6 previous case report of malignant glomus tumor in the hand. Although large and deeply
located glomus tumors are considered to be malignant, evidence has shown that most of these cases were clinically
benign. These lesions are better considered as glomus tumor of uncertain malignant potential. Due to rarity of malignant
glomus tumor, decision for operative treatment must be based on few case reports. In this article we review the literature
for malignant glomus tumor of hand and their management, also we report a 49 year-old man with glomus tumor of
uncertain malignant potential in thumb who was treated by wide amputation
Level of evidence: IV

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Main Subjects