Topiramate-induced Neuropathy Mimicking Carpal Tunnel Syndrome: A Case Report

Document Type: CASE REPORT


1 Rutgers New Jersey Medical School, Newark, NJ

2 Rothman Institute, Division of Hand Surgery, Philadelphia, PA, USA


Carpel tunnel syndrome (CTS) is a condition in which median nerve compression results in paresthesias and pain in the
wrist and hand. We are going to report a rare case of topiramate-induced neuropathy which clinically resembles CTS.
Discontinuation of topiramate resulted in spontaneous resolution of numbness, paresthesia and pain in a few days. High
clinical suspicion is advised in patients who are on topiramate and present with signs of compressive neuropathy.


Main Subjects